| 产品详情 |
| Edit |   |
|---|
| Product Name | TRAIL, Recombinant, Human (APO 2 Ligand, TNF-Related Apoptosis-Inducing Ligand) |
|---|
| Description | Purity ~97% (RP-HPLC, SDS-PAGE). TNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family. In humans, the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL binds to the death receptors, DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. Source: Recombinant protein corresponding to human TRAIL, a single, non-glycosylated polypeptide chain containing 168aa, expressed in E. coli. Molecular Weight: ~19.6kD Biological Activity: Determined by the ability to induce apoptotic cell death in TRAIL-sensetive U343MG cells, ED50 for this effect is 1-3ng/ml. AA Sequence: The sequence of the first five N-terminal amino acids was determined and was fo |
|---|
| Size | 10ug, 50ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 299545 |
|---|
| Price | |
|---|
| Order / More Info | TRAIL, Recombinant, Human (APO 2 Ligand, TNF-Related Apoptosis-Inducing Ligand) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|