| 产品详情 |
| Edit |   |
|---|
| Product Name | TRAIL-R1,Fc, Recombinant, Human |
|---|
| Description | Purity >95% (SDS-PAGE). TRAIL-R1 (DR4; CD261) is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB. Biological Activity: Blocks human or mouse TRAIL activity in a concentration of 1-10ug/ml. Sequence: The extracellular domain of human TRAIL-R1 (aa 24-239) is fused to the Fc portion of human IgG1. |
|---|
| Size | 50ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | TRAIL-R1,Fc, Recombinant, Human (DR4, TNFRSF 10A, APO2, CD261, TRAIL Receptor 1, TNF-related Apoptosis-inducing Ligand Receptor 1) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 45353 |
|---|
| Price | |
|---|
| Order / More Info | TRAIL-R1,Fc, Recombinant, Human from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|