| 产品详情 |
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| Product Name | PCBP1, Recombinant, Human, aa1-163, His-Tag (Poly(rC) binding protein 1) |
| Description | Purity ~85% (SDS-PAGE). PCBP1 appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promotes poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. PCBP1 is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. Source: Recombinant protein corresponding to aa1-163 of human PCBP1, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~19.6kD AA |
| Size | 100ug, 500ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | Accession: NP_006187 |
| Catalog # | 350153 |
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| Order / More Info | PCBP1, Recombinant, Human, aa1-163, His-Tag (Poly(rC) binding protein 1) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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