产品名称 Bischloroanthrabenzoxocinone from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H10696
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameBischloroanthrabenzoxocinone
DescriptionPurity >99%. Bacterial type II fatty acid synthesis (FAS-II) is mediated by a series of enzymes, each of which may be targeted by potential antibiotics. Bischloroanthrabenzoxocinone (BABX) is an inhibitor of FAS-II, blocking fatty acid synthesis in S. aureus and E. coli with IC50 values of 11.4 and 35.3 µg/ml, respectively. It inhibits the growth of S. aureus and permeable E. coli strains with minimum inhibitory concentrations ranging from 0.2-0.4 µg/ml. BABX also displays binding to liver X receptors (LXRs), inhibiting agonist binding in an LXRAlpha-scintillation proximity assay (IC50 = 10 µM).
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Other Names(6R,16R)-10,12-dichloro-6,7,9,16-tetrahydro-11,13,15-trihydroxy-3-methoxy-1,6,9,9-tetramethyl-6,16-epoxy-14H-anthra[2,3-d][1]benzoxocin-14-one, (-)-Bischloroanthrabenzoxocinone, BABX
Gene, Accession, CAS #CAS: 866022-28-8
Catalog #LS-H10696
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Order / More InfoBischloroanthrabenzoxocinone from LIFESPAN BIOSCIENCES INC.
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