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| Product Name | Gp130, Human, BioAssay™ MAP Kit (CD130, IL6ST) |
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| Description | Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R. Sample Type: Cell culture supernates, serum, EDTA plasma, and heparin plasma. Sensitivity: The mean MDD was 12.0pg/ml. The Minimum Detectable Dose (MDD) was determined by adding two standard deviations to the MFI of twenty zero standard replicates and calculating the corresponding concentration. Range: ~4.96-21pg/ml Specificity: Recognizes natural and recombinant human gp130. Test Principle: Human gp130 BioAssay™ Kit afford the u |
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| Size | 1 kit |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 145741 |
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| Order / More Info | Gp130, Human, BioAssay™ MAP Kit (CD130, IL6ST) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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