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| Product Name | SRPK1, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). SRPK1 is a Ser/Thr protein kinase that has sequence and function similar to SRPK2. In human cancer cells, it was observed that inactivation of SRPK1 induces cellular resistance to anticancer drugs such as cisplatin and bleomycin. SRPK1 phosphorylates serine/arginine-rich (SR) proteins, such as splicing factors ASF/SF2, SC35, and SRp55, in their arginine/serine-rich (RS) domains in vitro. Hence it is believed that SRPK1 plays a key role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Source: Recombinant protein corresponding to human SRPK1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~130kD Specific Activity: 196nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SRPK1, Recombinant, Human, GST-Tag (SRSF Protein Kinase 1, SFRS Protein Kinase 1, Serine/Arginine-rich Protein-specific Kinase 1, SFRSK1) |
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| Gene, Accession, CAS # | Accession: BC038292 |
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| Catalog # | 500460 |
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| Order / More Info | SRPK1, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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