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| Product Name | SRPK2, Recombinant, Human, GST-Tag (SRSF Protein Kinase 2, SFRSK2, FLJ36101) |
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| Description | Purified (~70-90%). SRPK2 is a member of the serine/arginine (SR) protein-specific kinase family that are cell cycle-regulated protein kinases which phosphorylate SR domain-containing proteins in nuclear speckles and mediate the pre-mRNA splicing events. SRPK2 knock down results in hypophosphorylation of the serine/arginine domain-containing human PRP28 protein thereby destabilizing PRP28 association with the tri-snRNP. RNAi-mediated depletion in HeLa cells showed that SRPK2 is essential for cell viability, and it is required for spliceosomal B complex formation. Source: Recombinant protein corresponding to human SRPK2, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~135kD Specific Activity: 155nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_182691 |
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| Catalog # | 500461 |
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| Order / More Info | SRPK2, Recombinant, Human, GST-Tag (SRSF Protein Kinase 2, SFRSK2, FLJ36101) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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