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| Antigenic Specificity | Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (aa 458-474) |
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| Clone | S10-7 |
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| Host Species | Mouse |
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| Reactive Species | hamster, human, mouse, rat |
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| Isotype | n/a |
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| Format | allophycocyanin (APC) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry (ICC),Immunofluorescence (IF),Immunohistochemistry (IHC),Immunoprecipitation (IP),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This gene encodes a member of the beta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein described in this record plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. |
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| Immunogen | Synthetic peptide amino acids 458-474 of rat CavB4 |
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| Other Names | CACNB4|CAB4|CACNLB4|EA5|EIG9|EJM|EJM4|EJM6|3110038O15Rik|Cchb4|lethargic|lh |
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| Gene, Accession # | Gene ID: 785,12298,58942 |
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| Catalog # | ABIN2485258 |
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| Price | |
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| Order / More Info | Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) (aa 458-474) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 17664337 |
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