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| Product Name | Recombinant Human Activated RNA polymerase II transcriptional coactivator p15 |
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| Description | 2-127aa; Full Length. MW: 30.2kD. Purity >90% as determined by SDS-PAGE. General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Positive cofactor 4; PC4; SUB1 homolog; p14] |
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| Gene, Accession, CAS # | SUB1, Gene ID: 10923, Accession: NP_006704.3 |
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| Catalog # | MBS962922 |
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| Order / More Info | Recombinant Human Activated RNA polymerase II transcriptional coactivator p15 from MYBIOSOURCE INC. |
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| Product Specific References | A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators.Kretzschmar M., Kaiser K., Lottspeich F., Meisterernst M.Cell 78:525-534(1994) Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes.Ge H., Roeder R.G.Cell 78:513-523(1994) Phosphorylation negatively regulates the function of coactivator PC4.Ge H., Zhao Y., Chait B.T., Roeder R.G.Proc. Natl. Acad. Sci. U.S. |
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