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| Product Name | Brevican, Recombinant, Human (BEHAB, Brain-Enriched Hyaluronan Binding Protein) |
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| Description | Purity ≥ 85%, as determined by SDS-PAGE and visualized by silver stain. Brevican, also called BEHAB, is a secreted member of the the lectican family of proteoglycans that share a common domain structure. Brevican contains an Ig-like V-set domain, two link domains, a Glu-rich region, a central region with glycosaminoglycan (GAG) modifications, an EGF-like domain, a C-type lectin domain, and a C-terminal Sushi/CRP-like domain. Brevican is restricted to the CNS and is expressed by astrocytes, oligodendrocytes, and neurons. A GPI-anchored alternate splice form exists that is truncated following the central (GAG) region. Brevican is cleaved by multiple proteases and exists in a number of distinct fragments. Full-length brevican consists of a 97kD core protein with up to approximately 100kD of attached chondroitin sulfate but not heparan sulfate chains. Brevican associates with the extracellular matrix, perineuronal nets, and astrocyte cell surfaces by means of its chondroitin sulfate, GPI a |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: AAH09117 |
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| Catalog # | B2739-71 |
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| Order / More Info | Brevican, Recombinant, Human (BEHAB, Brain-Enriched Hyaluronan Binding Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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