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| Product Name | H 1152 dihydrochloride |
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| Description | Rho-kinase (ROCK) inhibitor that displays high selectivity over other protein kinases (IC50 values are 0.012, 0.180, 0.360, 0.745, 3.03, 5.68 and 28.3 μM for ROCKII, CAMKII, PKG, Aurora A, PKA, PKC and MLCK respectively). Inhibits sulprostone-induced contractions in guinea pig aorta (IC50 = 190 nM) and displays proerectile effects in rats. Glycyl Derivative also available.. Purity 98%. MW (observed): 392.34 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride |
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| Gene, Accession, CAS # | CAS: 871543-07-6 |
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| Catalog # | 2414/1 |
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| Order / More Info | H 1152 dihydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 19828812, 22689969, 24284827, 25735303, 26148352, 27799301, 28031255, 28065575, 28486133, 29170395 |
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