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| Product Name | PI4K2A, Recombinant, Human, GST-Tag (Phosphatidylinositol 4-Kinase Type 2 Alpha, PI4KII, PIK42A) |
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| Description | Purified (~70-90%). PI4K2A or phosphatidylinositol 4-kinase type 2 alpha is involved in the formation of phosphatidylinositolpolyphosphates (PtdInsPs) which are centrally involved in many biologic processes ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4K2A phosphorylates PtdIns at the D-4 position which is an essential step in the biosynthesis of PtdInsPs. PI4K2A is a novel regulator of tumor growth by its action on angiogenesis and HIF-1alpha regulation. PI4K2A generates PtdIns4P-rich domains within the Golgi which regulate targeting of clathrin adaptor AP-1 complexes. PI4K2A is also required for Wnt to regulate LRP6 phosphorylation. Source: Recombinant protein corresponding to human PI4K2A, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~79kD Specific Activity: 95nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_018425 |
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| Catalog # | 500367 |
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| Order / More Info | PI4K2A, Recombinant, Human, GST-Tag (Phosphatidylinositol 4-Kinase Type 2 Alpha, PI4KII, PIK42A) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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