| 产品详情 |
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| Product Name | PI4KB, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). PI4KB is a member of the phosphatidylinositol 4-kinase family (PI4K) and is the first committed step in the production of the second messenger inositol-1,4,5-trisphosphate (PIP3). PI4KB regulates the golgi disintegration/reorganization during mitosis possibly via the phosphorylation of phosphatidylinositol. PI4KB is a type III enzyme that is sensitive to wortmannin and is responsible for regulating the synthesis of agonist-sensitive pools of polyphosphoinositides. PI4KB is critical for glucose-induced insulin secretion due to its capacity to regulate the release of secretory granules. PI4KB inhibits the insulin-stimulated translocation of glucose transporter-4 in mouse adipocytes through its interaction with neuronal calcium sensor-1. Source: Recombinant protein corresponding to human PI4KB fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~120kD Biological Activity: 37nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PI4KB, Recombinant, Human, GST-Tag (Phosphatidylinositol 4-kinase beta, PI4K-BETA, pi4K92, PI4Kbeta, PI4KIIIbeta) |
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| Gene, Accession, CAS # | Accession: BC000029, SwissProt: Q9UBF8 |
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| Catalog # | 500369 |
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| Order / More Info | PI4KB, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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