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| Product Name | PARP3, Recombinant, Human, His-Tag |
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| Description | Purity ~98% (SDS-PAGE). PARP-3 [ARTD3] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing. Source: Recombinant protein corresponding to full length human PARP-3, fused to a HA-tag and a His-tag, expressed in Sf21 cells. Biological Activity: ~10U/mg protein (only monoADP-ribosyl transferase activity) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | PARP3, Recombinant, Human, His-Tag (Poly [ADP-ribose] Polymerase 3, PARP-3, hPARP-3, IRT1, NAD(+) ADP-ribosyltransferase 3, ADPRT-3, Poly[ADP-ribose] Synthase 3, pADPRT-3, ADPRT3, ADPRTL3) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 207331 |
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| Order / More Info | PARP3, Recombinant, Human, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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