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| Product Name | RAF1, Active, Recombinant, Human |
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| Description | Purity ~85% (SDS-PAGE). RAF1 is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. The activated RAF1 can phosphorylate and activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Source: Recombinant protein corresponding to human RAF1 expressed in Sf9 insect cells. Molecular Weight: ~63.0kD Biological Activity: The specific activity of RAF1(EE) was determined to be ~6000 nmol/min/mg in a coupled assay as per activity assay protocol. |
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| Size | 5ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | RAF1, Active, Recombinant, Human (raf-1, raf 1, Active RAF1, RAF1, RAF, human RAF, active kinase, active kinases, recombinant RAF1, recombinant RAF, kinase activity assay, protein kinase) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 167952 |
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| Order / More Info | RAF1, Active, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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