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| Product Name | RAF1, Recombinant, Human, GST-Tag (NS5, CRAF, Raf-1, c-Raf) |
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| Description | Purified (~70-90%). RAF1 is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. The activated RAF1 can phosphorylate and activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Source: Recombinant protein corresponding to human RAF1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~63kD Specific Activity: ~6000nmol/min/mg in a coupled assay as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_002880 |
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| Catalog # | 500417 |
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| Order / More Info | RAF1, Recombinant, Human, GST-Tag (NS5, CRAF, Raf-1, c-Raf) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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