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| Product Name | uBE2N, 1-152aa, Human, His tag, E Coli |
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| Description | MW: 19.3 kDa (172aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. uBE2N, also known as uBC13, is a member of the E2 ubiquitin-conjugating enzyme family. It catalyzes the ATP-dependent synthesis of non-canonical polyubiquitin chains, a process that does not lead to proteasomal degradation. It mediates the transcription of several target genes and is thought to play a role in cell cycle progression; cellular differentiation and DNA repair mechanisms that ensure cell survival after DNA damage. |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [ubiquitin-conjugating enzyme E2 N; MGC131857; MGC8489; uBC13; ubcH-ben] |
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| Gene, Accession, CAS # | uBE2N, Gene ID: 7334, Accession: NP_003339 |
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| Catalog # | MBS203915 |
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| Order / More Info | uBE2N, 1-152aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Yamaguchi T. et al. (1996) J Biochem., 120:494-497.; Yamamoto M. et al. (2006) Nat. Immunol. 7: 962-970. |
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