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| Product Name | Hepatitis B Virus Core, Recombinant, Yeast, aa1-186 (HBV Core) |
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| Description | Purity ~90% (10% PAGE, coomassie staining). Hepatitis B is one of a few known non-retroviral viruses which employ reverse transcription as a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA. Source: Recombinant protein corresponding to the HBV core immunodominant region, |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208969 |
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| Order / More Info | Hepatitis B Virus Core, Recombinant, Yeast, aa1-186 (HBV Core) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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