| 产品详情 |
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| Product Name | IBMX (3-Isobutyl 1-methylxanthine, NSC 165960, SC2964, EINECS 249-259-3) |
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| Description | Purity ≥ 99% (HPLC). Cell permeable, competitive, non-specific cAMP and cGMP phosphodiesterase inhibitor. Increases cAMP levels that activate PKA, leading to decreased proliferation, increased differentiation and induction of apoptosis. Enhances differentiation of 3T3-L1 cells. Non-selective adenosine receptor antagonist. Inhibits Ca2+ ion channels. Activates TNF-alpha. Adipogenic. Activates leukotriene synthesis. Reduces inflammation and innate immunity. IC50 values are 13, 18, 19, 32 and 50uM for PDE4, PDE3, PDE1, PDE5 and PDE2 respectively Solubility: DMSO, Dichloromethane, Ether, Ethyl acetate, Methanol and ethanol. Insoluble in water. |
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| Size | 500mg, 1g |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-Isobutyl 1-methylxanthine, NSC 165960, EINECS 249-259-3 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 44890 |
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| Order / More Info | IBMX (3-Isobutyl 1-methylxanthine, NSC 165960, SC2964, EINECS 249-259-3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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