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Product Name | CALP1 |
Description | Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA and HIV-1 gp120-activated channels, inhibiting Ca2+-mediated cytotoxicity and apoptosis (IC50 = 52 μM). Shown to protect pancreatic acinar cells from gossypol (Cat.No. 1964) induced necrosis. Inhibits VLA-5-mediated adhesion of mast cells to fibronectin in vitro and attenuates inflammatory cell influx in guinea pig lung in vivo. MW (observed): 842.09. |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Calcium-like peptide 1 |
Gene, Accession, CAS # | CAS: 145224-99-3 |
Catalog # | 2090/1 |
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Order / More Info | CALP1 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 22886848, 28252652 |
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