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| Product Name | CRK, Recombinant, Human (Adapter Molecule crk, Proto-oncogene c-Crk, p38) |
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| Description | Purity ~95% (SDS-PAGE). CRK is a member of signaling adapter protein family that binds to several tyrosine-phosphorylated proteins. This protein is involved in many cellular processes including apoptosis, proliferation, and differentiation. It has a modular domain architecture consisting of an SH2 followed by two SH3 domains (src-homology domains). The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Source: Recombinant corresponding to aa1-204 of human CRK protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MAGNFDSEER SSWYWGRLSR QEAVALLQGQ RHGVFLVRDS STSPGDYVLS VSENSRVSHY IINSSGPRPP VPPSPAQPPP GVSPSRLRIG DQEFDSLPAL LEFYKIHYLD TTTLIEPVSR SRQGSGVILR QEEAEYVRAL FDFNGNDEED LPFKKGDILR IRDKPEEQWW NAEDSEGKRG MIPVPYVEKY RPASASVSAL IGGR Molecular Weight: 25kD (224aa) confirmed by MALDI-TOF |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_005197 |
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| Catalog # | C7924-11 |
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| Order / More Info | CRK, Recombinant, Human (Adapter Molecule crk, Proto-oncogene c-Crk, p38) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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