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| Product Name | BMI1, Recombinant, Human, aa1-250, GST-Tag (Polycomb Complex Protein BMI-1) |
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| Description | Purity ~90% (SDS-PAGE). Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. Source: Recombinant protein corresponding to aa1-250 from human BMI1, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~56.4kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Polycomb group RING finger protein 4, RING finger protein 51 |
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| Gene, Accession, CAS # | SwissProt: P35226 |
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| Catalog # | 372460 |
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| Order / More Info | BMI1, Recombinant, Human, aa1-250, GST-Tag (Polycomb Complex Protein BMI-1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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