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| Product Name | EHMT2, Active |
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| Description | 807-end. MW: ~75 kDa. Description: Recombinant human EHMT2 (807-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: EHMT2 is a lysine-preferring histone methyltransferase. EHMT2 can methylate itself at K165 and this automethylation is necessary and sufficient to mediate in vivo interaction of EHMT2 with heterochromatin protein-1 (HP1) (1). EHMT2 is responsible for the majority of dimethylation of histone H3 at lysine 9 (H3K9me2) and is req |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Methyltransferase Assay |
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| Other Names | [Homo sapiens euchromatic histone lysine methyltransferase 2 (EHMT2), transcript variant 2, mRNA; Histone-lysine N-methyltransferase EHMT2; histone-lysine N-methyltransferase EHMT2; euchromatic histone lysine methyltransferase 2; Euchromatic histone-lysine N-methyltransferase 2; HLA-B-associated transcript 8; Histone H3-K9 methyltransferase 3; H3-K9-HMTase 3; Lysine N-methyltransferase 1C; Protein G9a] |
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| Gene, Accession, CAS # | EHMT2, Gene ID: 10919, Accession: NM_006709.4 |
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| Catalog # | MBS515494 |
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| Order / More Info | EHMT2, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Sampath, S C. et al: Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assembly. Molec. Cell 27: 596-608, 2007. 2. Lehnertz B. et al: Activating and inhibitory functions for the histone lysine methyltransferase G9a in T helper cell differentiation and function. J Exp Med. 2010 May 10;207 (5):915-22. |
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