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| Product Name | Human Soluble Interleukin 2 Receptor Alpha (sIL2Ra) Protein (Recombinant) |
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| Description | Purity >98% by SDS-PAGE gel and HPLC analyses., MW: 24.8 kDa or 40-50 kDa. The IL-2 receptor system consists of three non-covalently linked subunits termed IL-2Ra, IL-2Rβ, and IL-2R?. The IL-2Ra is a type I transmembrane protein consisting of a 219 amino acid extracellular domain, a 19 amino acid transmembrane domain and a 13 amino acid intracellular domain, which is not involved in the transduction of IL-2 signals. Proteolytic processing of IL-2Ra releases the entire extracellular domain of IL-2Ra, thereby generating a 219 amino acid soluble protein called soluble IL-2Ra (sIL-2Ra). The homodimeric form binds IL-2 (KD=10mM) and facilitates IL-2 signaling. The secreted sIL-2Ra is expressed on leukemia cells, lymphoma cells, and newly activated T and B cells, as well as on approximately 10% of NK cells. Recombinant Human sIL-2 Receptor a is a 24.8 kDa protein containing 219 amino acid residues consisting of only the extracellular domain of IL-2Ra. As a result of glycosylation, Recombinant Human sIL-2 Receptor a migrates with an apparent molecular mass of approximately 40-50 kDa by SDS-PAGE gel, under reducing and non-reducing conditions. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-G133795 |
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| Order / More Info | Human Soluble Interleukin 2 Receptor Alpha (sIL2Ra) Protein (Recombinant) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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