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| Product Name | Recombinant Human DNA repair protein complementing XP-C cells |
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| Description | 496-734aa; Partial. MW: 31.6kD. Purity >90% as determined by SDS-PAGE. Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly scree |
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| Size | 0.05 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli), 1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Xeroderma pigmentosum group C-complementing proteinp125] |
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| Gene, Accession, CAS # | XPC, Gene ID: 7508, Accession: NP_004619.3 |
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| Catalog # | MBS960949 |
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| Order / More Info | Recombinant Human DNA repair protein complementing XP-C cells from MYBIOSOURCE INC. |
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| Product Specific References | Purification and cloning of a nucleotide excision repair complex involving the Xeroderma pigmentosum group C protein and a human homologue of yeast RAD23.Masutani C., Sugasawa K., Yanagisawa J., Sonoyama T., Ui M., Enomoto T., Takio K., Tanaka K., van der Spek P.J., Bootsma D., Hoeijmakers J.H.J., Hanaoka F.EMBO J. 13:1831-1843(1994) The human XPC DNA repair genearrangement, splice site information content and influence of a single nucleotide polymorphism in a splice acceptor site on alternative |
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