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| Product Name | Recombinant Human DNA repair protein XRCC3 |
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| Description | 1-316aa; Full Length. MW: 53.83kD. Purity >90% as determined by SDS-PAGE. Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the RAD21 paralog protein complex CX3 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, CX3 acts downstream of RAD51 recruitment; the complex binds predominantly to the intersection of the four duplex arms of the Holliday junction (HJ) an |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [X-ray repair cross-complementing protein 3] |
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| Gene, Accession, CAS # | XRCC3, Gene ID: 7517, Accession: NP_001093588.1 |
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| Catalog # | MBS1122399 |
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| Order / More Info | Recombinant Human DNA repair protein XRCC3 from MYBIOSOURCE INC. |
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| Product Specific References | XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages.Liu N., Lamerdin J.E., Tebbs R.S., Schild D., Tucker J.D., Shen M.R., Brookman K.W., Siciliano M.J., Walter C.A., Fan W., Narayana L.S., Zhou Z.-Q., Adamson A.W., Sorensen K.J., Chen D.J., Jones N.J., Thompson L.H.Mol. Cell 1:783-793(1998) NIEHS SNPs program Identification and purification of two distinct complexes containing the five RAD51 paralogs.Masson J.Y., Tar |
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