| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD46 |
|---|
| Clone | MEM-258 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | Flo, IP, WB |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD46 Antibody (clone MEM-258) LS-C204148. Specificity: CD46 antigen (human). The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. |
|---|
| Immunogen | HPB-ALL cells. |
|---|
| Other Names | CD46, AHUS2, CD46 antigen, MCP, Measles virus receptor, TLX, MIC10, TRA2.10, Membrane cofactor protein |
|---|
| Gene, Accession # | CD46, Gene ID: 4179 |
|---|
| Catalog # | LS-C204148 |
|---|
| Price | |
|---|
| Order / More Info | CD46 Antibody from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|