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| Product Name | Nocodazole Solution in DMSO, 5mg/ml |
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| Description | Nocodazole: ≥99% (HPLC); DMSO: ≥99.9%. Nocodazole, an inhibitor of microtubule formation, was found to greatly inhibit cell division around the mound stage as well as during the vegetative growth phase, when applied to exponentially growing Ax-2 cells. Mitotic arrest of cells with nocodazole can be used to study phosphorylation of microtubule-associated proteins which increase during mitosis, concomitant with increased microtubule dynamics. Nocodazole has been found to dramatically inhibit T cell antigen receptor (TCR) signaling, independently of its ability to depolymerize microtubules. Nocodazole arrests the cell cycle at G2/M phase and prevents phosphorylation of the T cell antigen receptor and inhibits its activity. Appearance: Supplied as a liquid. Purity: Nocodazole: ≥99% (HPLC); DMSO: ≥99.9% Method for Determining Identity: Proton NMR Spectroscopic Analysis Usage: Use stock solution at 5mg/ml in DMSO. Further dilutions can be made in culture media. Due to insolubility (nocodazole is only slightly soluble in water), n |
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| Size | 1ml, 5ml, 10ml |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Methyl N-(5-thenoyl-2-benzimidazolyl)carbamate; Methyl [5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate; Oncodazole; R 17934; [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid methyl ester |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N3000-01 |
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| Order / More Info | Nocodazole Solution in DMSO, 5mg/ml from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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