| 产品详情 |
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| Product Name | Recombinant Human Homer protein homolog 1 |
| Description | 1-354. MW: 67.7kD. Purity >90% as determined by SDS-PAGE. Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 ac |
| Size | 0.05 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli), 1 mg (E-Coli) |
| Concentration | n/a |
| Applications | n/a |
| Other Names | [homer protein homolog 1 isoform 2; Homer protein homolog 1; homer protein homolog 1; homer scaffolding protein 1] |
| Gene, Accession, CAS # | HOMER1, Gene ID: 9456, Accession: NP_001264006.1 |
| Catalog # | MBS717400 |
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| Order / More Info | Recombinant Human Homer protein homolog 1 from MYBIOSOURCE INC. |
| Product Specific References | Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.Xiao B., Tu J.C., Petralia R.S., Yuan J.P., Doan A., Breder C.D., Ruggiero A., Lanahan A.A., Wenthold R.J., Worley P.F.Neuron 21:707-716(1998) |
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