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| Product Name | FGF-1 |
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| Description | Purity ~95% (SDS-PAGE). Fibroblast growth factors (FGFs) constitute a family of heparin-binding polypeptides involved in the regulation of biological responses such as growth, differentiation and angiogenesis. The biological effects of FGFs are me-diated by four structurally related receptor tyrosine kinases denoted FGFR1, FGFR2, FGFR3 and FGFR4. FGF-1 [FGF-acidic; ECGF; HBGF-1] is a powerful mitogen of cells of mesodermal, ectodermal and endodermal origin. FGF-1 association with heparan sulfate is a prerequisite for activation of FGF receptors. FGF-1 plays a role in var- ious stages of development and morphogenesis as well as in angiogenesis and wound healing processes. Recent data indicate a role of FGF-1 in inflammation and obesity. FGF-1 is selectively induced in fat cells by high-fat diet feeding and established the PPARy-FGF-1 axis as a critical pathway that regulates adipose tissue remodeling. Source: Recombinant protein corresponding to aa16-155 from human FGF-1, expressed in E |
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| Size | 10ug, 3x10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FGF-1 (Fibroblast Growth Factor 1, Acidic Fibroblast Growth Factor, Endothelial Cell Growth Factor, ECGF, Heparin-binding, Growth Factor 1, HBGF-1) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 207177 |
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| Order / More Info | FGF-1 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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