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| Product Name | PI 103 hydrochloride |
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| Description | Inhibitor of DNA-PK, PI 3-kinase (p110α) and mTOR (IC50 values are 2, 8, 20, 26, 48, 83, 88, 150, 850, 920, ~ 1000 and 2300 nM for DNA-PK, p110α, mTORC1, PI 3-KC2β, p110δ, mTORC2, p110β, p110γ, ATR, ATM, PI 3-KC2α and hsVPS34 respectively). Inhibits growth of human tumor xenografts in mice in vivo. Induces autophagosome formation in glioma cells. Purity 98%. MW (observed): 384.82 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-[4-(4-Morpholinylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol hydrochloride |
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| Gene, Accession, CAS # | CAS: 371935-79-4 |
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| Catalog # | 2930/50 |
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| Order / More Info | PI 103 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21685895, 23077641, 23382862, 23963679, 24395886, 25187540, 25347447 |
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