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| Product Name | Recombinant Human CD59 glycoprotein |
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| Description | 26-102aa; Full Length. MW: 36.4kD. Purity >90% as determined by SDS-PAGE. Potent inhibitor of the complent membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complents of the assbling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine re |
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| Size | 0.01 mg (E-Coli), 0.01 mg (Yeast), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [1F5 antigen20 kDa homologous restriction factor; HRF-20; HRF20; MAC-inhibitory protein; MAC-IP; MEM43 antigen; Membrane attack complex inhibition factor; MACIF; Membrane inhibitor of reactive lysis; MIRL; Protectin; CD59] |
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| Gene, Accession, CAS # | CD59, Gene ID: 966, Accession: NP_000602.1 |
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| Catalog # | MBS953357 |
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| Order / More Info | Recombinant Human CD59 glycoprotein from MYBIOSOURCE INC. |
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| Product Specific References | CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.Davies A., Simmons D.L., Hale G., Harrison R.A., Tighe H., Lachmann P.J., Waldmann H.J. Exp. Med. 170:637-654(1989) |
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