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| Product Name | Delta-actitoxin-Avd1c, Recombinant, Anemonia Sulcata, aa1-47, His-tag |
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| Description | Purity ~90% (SDS-PAGE). Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation. Has a strong effect on crustaceans and insects (DmNav1) and a weaker effect on mammals. This toxin is highly potent at mammalian Nav1.1/SCN1A (EC(50)=6.01 nM) and Nav1.2/SCN2A (EC(50)=7.88 nM) (PubMed:15169781). It has also great activity on Nav1.5/SCN5A (EC(50)=49.05 nM), Nav1.4/SCN4A (EC(50)=109.49 nM) and Nav1.6/SCN8A (EC(50)=about 180 nM) and is less potent on Nav1.3/SCN3A (EC(50)=759.22 nM) (when measured as the increase in the slow component) (PubMed:15169781). Source: Recombinant protein corresponding to aa1-47 from Anemonia Sulcata Delta-actitoxin-Avd1c, fused to His-tag at N-terminal, expressed in Yeast. Molecular Weight: ~6.9kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Neurotoxin 2, Anemonia viridis toxin 2, Av2, As2 Toxin ATX-II, Toxin II |
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| Gene, Accession, CAS # | SwissProt: P01528 |
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| Catalog # | 405904 |
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| Order / More Info | Delta-actitoxin-Avd1c, Recombinant, Anemonia Sulcata, aa1-47, His-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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