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Product Name | Recombinant Human E-Selectin Protein |
Description | Selectins are a family of calcium-dependent type 1 transmembrane proteins. Endothelial (E)-selectin is a heavily glycosylated transmembrane protein expressed by activated endothelial cells in microvascular linings. E-selectin, along with P-selectin and L-selectin, initiate recruitment of circulating leukocytes from blood to sites of inflammation in the vascular lining through interaction with specific cell surface associated carbohydrate determinants. E-selectin consists of an N-terminal type 1 lectin domain, an EGF-like domain, 6 sushi (CCP/SCR) domains, a transmembrane sequence, and a short cytoplasmic domain. Recombinant human E-selectin is a 58.6 kDa protein containing 535 amino acid residues, corresponding to the extracellular portion of the full length protein. Due to glycosylation, E-selectin migrates at an apparent molecular weight of approximately 65-85 kDa by SDS-PAGE analysis under reducing conditions. |
Size | Various Sizes |
Concentration | n/a |
Applications | Cell Culture |
Other Names | E-selectin;CD62 antigen-like family member E;Endothelial leukocyte adhesion molecule 1;ELAM-1;Leukocyte-endothelial cell adhesion molecule 2;LECAM2;CD62E;SELE;ELAM1; Endothelial leukocyte adhesion molecule 1 (ELAM1), CD62E, SELE |
Gene, Accession, CAS # | SELE, UniProt: P16581 |
Catalog # | PROTP16581-2 |
Price | |
Order / More Info | Recombinant Human E-Selectin Protein from BOSTER BIO |
Product Specific References | n/a |
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