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| Product Name | LOX, 169-417aa, Human, His tag, E Coli (Denatured) |
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| Description | MW: 31.4 kDa (272aa). Purity >85% by SDS-PAGE. LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL ty |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Protein-lysine 6-oxidase; Lysyl oxidase] |
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| Gene, Accession, CAS # | LOX, Gene ID: 4015, Accession: NP_002308 |
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| Catalog # | MBS205887 |
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| Order / More Info | LOX, 169-417aa, Human, His tag, E Coli (Denatured) from MYBIOSOURCE INC. |
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| Product Specific References | Kim Y., et al. (1995) J. Biol. Chem. 270:7176-7182.; Contente S., et al. (1999) Mol. Cell. Biochem. 194:79-91. |
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