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| Product Name | GOPC, Recombinant, Human, His-Tag |
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| Description | Purity ~90% (SDS-PAGE). GOPC, also known as PIST, is a PDZ domain-containing Golgi protein. This protein functions as a homooligomer that interacts with a variety of proteins and plays a role in intracellular protein trafficking and degradation. Additionally, GOPC is thought to regulate ionic currents via membrane channel modification and may also play a role in autophagy. Chromosomal aberrations in the gene encoding GOPC are found in glioblastoma multiform (GBM), a common and aggressive form of brain tumor, suggesting a role for mutated PIST in carcinogenesis. Recombinant GOPC protein was expressed in E.coli and purified by using conventional chromatography techniques. Source: Recombinant protein corresponding to aa278-454 from human GOPC, expressed in E.coli. Molecular Weight: ~21.5kD (MALDI-TOF) (Molecular weight on SDS-PAGE will appear higher) AA Sequence: MGSSHHHHHH SSGLVPRGSH MIRKVLLLKE DHEGLGISIT GGKEHGVPIL ISEIHPGQPA DRCGGLHVGD AILAVNGVNL RDTKHKEAVT ILSQQRGEIE FEVVYVAPEV DSDDEN |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GOPC, Recombinant, Human, His-Tag (Golgi-associated PDZ and Coiled-coil Motif-containing Protein, PDZ Protein Interacting Specifically with TC10, CFTR-associated Ligand, Fused in Glioblastoma, PIST, CAL, FIG) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 138003 |
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| Order / More Info | GOPC, Recombinant, Human, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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