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| Product Name | GOPC-ROS1 Mutant, Active |
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| Description | 1-419 (GOPC) - 1881-end (ROS1). MW: 145 kDa. Description: Recombinant human fusion protein GOPC (1-419)-ROS1 (1881-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: GOPC gene encodes a Golgi protein with a PDZ domain. Mice which are deficient in the GOPC protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms of GOPC have been found for this gene and GOPC gene locus is involved in transloc |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Kinase Assay |
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| Other Names | [Homo sapiens golgi associated PDZ and coiled-coil motif containing (GOPC), transcript variant 1, mRNA; Golgi-associated PDZ and coiled-coil motif-containing protein; Golgi-associated PDZ and coiled-coil motif-containing protein; golgi associated PDZ and coiled-coil motif containing; CFTR-associated ligand; Fused in glioblastoma; PDZ protein interacting specifically with TC10; PIST] |
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| Gene, Accession, CAS # | GOPC-ROS1, Gene ID: 57120, Accession: NM_020399.3 |
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| Catalog # | MBS515650 |
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| Order / More Info | GOPC-ROS1 Mutant, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Maxwell, M. et al: Overexpression of the ros1 gene in primary human gliomas may contribute to malignant progression. Int J Oncol. 1996 Apr;8 (4):713-8. 2. Suehara Y. et al: Identification of KIF5B-RET and GOPC-ROS1 fusions in lung adenocarcinomas through a comprehensive mRNA-based screen for tyrosine kinase fusions. Clin Cancer Res. 2012 Dec 15;18 (24):6599-608. |
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