产品详情 |
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Product Name | K 02288 |
Description | Potent and selective inhibitor of type I bone morphogenic protein (BMP) receptors (IC50 values are 1.1, 1.8, 6.4, 34.4, 220, 302 and 321 nM for ALK2, ALK1, ALK6, ALK3, ActRIIA, ALK4 and ALK5 respectively). Reduces BMP4-induced Smad1/5/8 phosphorylation in vitro (IC50 = 100 nM) and induces dorsalization of zebrafish embryos. Purity 99%. MW (observed): 352.38 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3-[(6-Amino-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenol. K 02288a |
Gene, Accession, CAS # | CAS: 1431985-92-0 |
Catalog # | 4986/10 |
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Order / More Info | K 02288 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 25706341 |
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