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| Product Name | TFB2M, 20-396aa, Human, His tag, E Coli |
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| Description | MW: 45.8 kDa (401aa) confirmed by MALDI-TOF. Purity >90% by SDS-PAGE. TFB2M is S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. This protein is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. TFB2M stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficie |
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| Size | 0.05 mg, 0.25 mg |
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| Concentration | 0.5 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [Dimethyladenosine transferase 2 mitochondrial; Dimethyladenosine transferase 2; mitochondrial; Hkp1; mtTFB2] |
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| Gene, Accession, CAS # | TFB2M, Gene ID: 64216, Accession: NP_071761 |
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| Catalog # | MBS204492 |
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| Order / More Info | TFB2M, 20-396aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Litonin,D.,et al. (2010) J. Biol. Chem. 285 (24), 18129-18133; Norrbom,J.,et al. (2010) Acta Physiol (Oxf) 198 (1), 71-79. |
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