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| Antigenic Specificity | Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (aa 400-450), (Extracellular Domain) |
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| Clone | polyclonal |
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| Host Species | Sheep |
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| Reactive Species | rat, mouse |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Function: Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.Subunit: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. Binds SH2B2. Interacts with SQSTM1 and ARMS.Subcellular location: Membrane, Single-pass type I membrane protein. Also known as: Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, GP145-TrkB/GP95-TrkB, Trk-B, BDNF/NT-3 growth factors receptor. |
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| Immunogen | A synthetic peptide from aa region 400-450 of the extracellular domain of mouse TrkB conjugated to an immunogenic carrier protein was used as the antigen. |
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| Other Names | trkb|trkb-b|xtrkb|si:ch211-220b11.1|trkB2|NTRK2|ntrk2|gp145-trkb|TRKB|GP145-TrkB|trk-B|AI848316|C030027L06Rik|Tkrb|trkB|RATTRKB1|TRKB1|Trk-B|TrkB |
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| Gene, Accession # | Gene ID: 18212,25054 |
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| Catalog # | ABIN351075 |
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| Price | |
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| Order / More Info | Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (aa 400-450), (Extracellular Domain) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 18034455, 16141072, 2160854, 2555172, 9148911, 1645620 |
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