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| Antigenic Specificity | Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (aa 71-90), (N-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Neurotrophic tyrosine kinase receptor type 1, also called Trk-A, is a protein that in humans is encoded by the NTRK1 gene. The NTKR1 gene encodes the neurotrophic tyrosine kinase-1 receptor and belongs to a family of nerve growth factor receptors whose ligands include neurotrophins. This gene is mapped to 1q23.1. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of mouse TrkA(71-90aa LYVENQQHLQRLEFEDLQGL), different from the related rat sequence by two amino acids. |
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| Other Names | trk|trka|TRKA|MTC|TRK|TRK1|Trk-A|p140-TrkA|C80751|Tkr|TrkA|Trk|CTRKA|trkA|CAPM1|CFTD|NEM1|OK/SW-cl.5|TM-5|TM3|TM30|TM30nm|TM5|TPMsk3|hscp30 |
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| Gene, Accession # | Gene ID: 18211,59109 |
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| Catalog # | ABIN1673621 |
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| Price | |
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| Order / More Info | Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (aa 71-90), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 11418861, 15260993, 11114882 |
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