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| Product Name | EPOR, Recombinant, Human, aa25-250, His-Tag (EPO-R, Erythropoietin Receptor) |
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| Description | Purity ~95% (SDS-PAGE). EPOR, also known as Erythropoietin receptor, mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, it dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. So it may also activate the LYN tyrosine kinase. Source: Recombinant protein corresponding to aa25-250 from human EPOR, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~25.6kD (232aa), 28-40kD (SDS-PAGE under reducing conditions.) Endotoxin: <1EU/1ug (determined by LAL method) Biological Activity: Measured by its ability to inhibit EPO dependent proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is ≤70ng/ml. AA |
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| Size | 10ug, 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_000112, SwissProt: P19235 |
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| Catalog # | 377801 |
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| Order / More Info | EPOR, Recombinant, Human, aa25-250, His-Tag (EPO-R, Erythropoietin Receptor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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