| 产品详情 |
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| Product Name | Epothilone A |
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| Description | Purity >95%. Epothilone A (Epo A) is a biologically active macrolide produced from the fermentation of the soil bacteria S. cellulosum that was discovered as a potent antimicrotubule agent. In competition assays, epo A binds to Beta-tubulin with a similar order of magnitude as the binding of paclitaxel to Beta-tubulin (IC50 s = 2.3 and 3.6 µM, respectively). Epo A is cytotoxic to human T-24 bladder carcinoma cells (IC50 = 0.05 µM in vitro ) but has poor pharmacological properties and is 2-fold less potent in stabilizing microtubules compared to epothilone B . |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (1S,16R)-7S,11S-dihydroxy-8,8,10R,12S-tetramethyl-3S-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione, Epo A |
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| Gene, Accession, CAS # | CAS: 152044-53-6 |
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| Catalog # | LS-H7680 |
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| Price | |
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| Order / More Info | Epothilone A from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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