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Antigenic Specificity | Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blotting (WB),Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cadherins are calcium-dependent cell adhesion proteins. The classic cadherin subfamily includes N-, P-, R-, B- and E-cadherins as well as about ten other members which are found in adherens junctions (AJ), E-cadherin is found at the junctions of epithelial cells. Besides mediating cell-cell adhesion through homophilic interactions, E-cadherin mediates contact inhibition of cell growth, and loss of E-cadherin is associated with tumorigenesis. E-cadherin expression is frequently down-regulated or extinguished in malignancy which strongly correlates with poor prognosis. |
Immunogen | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of outside membrane of E-Cadherin. |
Other Names | E-Cad|E-cadherin|XB-cadherin|XBcad|XTCAD-1|b-cadherin|cadherin-1|cdh1-a|cdhc-A|cdhp|hjmd|l-cam|lcam|pcad|uvo|uvomorulin|xb-cad|xcdh1|Arc1|AA960649|E-cad|Ecad|L-CAM|UVO|Um|Arc-1|CD324|CDHE|ECAD|LCAM|arc-1|cd324|cdhe|ecad|cdh1|si:dz180o5.2 |
Gene, Accession # | Gene ID: 999,12550 |
Catalog # | ABIN343630 |
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Order / More Info | Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 21209962 |
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