| 产品详情 |
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| Product Name | METTL11A, Recombinant, Human, aa1-223, His-SUMO-Tag (Alpha N-terminal Protein Methyltransferase 1A) |
| Description | Purity ~90% (SDS-PAGE). Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1. Source: Recombinant protein corresponding to aa1-223 from human NTMT1, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~41.4kD AA |
| Size | 10ug, 50ug, 100ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Alpha N-terminal protein methyltransferase 1A, Methyltransferase-like protein 11AN-terminal R, CC1 methyltransferaseX-Pro-Lys N-terminal protein methyltransferase 1A, NTM1A |
| Gene, Accession, CAS # | SwissProt: Q9BV86 |
| Catalog # | 374196 |
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| Order / More Info | METTL11A, Recombinant, Human, aa1-223, His-SUMO-Tag (Alpha N-terminal Protein Methyltransferase 1A) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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