产品详情 |
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Antigenic Specificity | H3F3A |
Clone | RM190 |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | Protein A purified |
Size | 25 µg |
Concentration | 1 mg/ml |
Applications | WB, ELISA, Multiplex |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit monoclonal antibody to detect Histone H3.3. Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a co |
Immunogen | A peptide corresponding to human Histone H3.3. |
Other Names | H3F3A, H3.3A, H3F3, H3F3B, H3.3B |
Gene, Accession # | Gene ID: 3021, Accession: P84243 |
Catalog # | A1140-25 |
Price | |
Order / More Info | H3F3A Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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