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| Product Name | Recombinant Human Collagen alpha-2(IV) chain protein |
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| Description | 1493-1712aa; Partial. MW: 28.3kD. Purity >90% as determined by SDS-PAGE. Type IV collagen is the major structural component of glomerular basent membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potent |
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| Size | 0.05 mg, 0.2 mg, 0.5 mg, 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [collagen alpha-2(IV) chain preproprotein; Collagen alpha-2(IV) chain; collagen alpha-2(IV) chain; collagen type IV alpha 2] |
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| Gene, Accession, CAS # | COL4A2, Gene ID: 1284, Accession: NP_001837.2 |
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| Catalog # | MBS953616 |
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| Order / More Info | Recombinant Human Collagen alpha-2(IV) chain protein from MYBIOSOURCE INC. |
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| Product Specific References | The complete primary structure of the alpha 2 chain of human type IV collagen and comparison with the alpha 1(IV) chain.Hostikka S.L., Tryggvason K.J. Biol. Chem. 263:19488-19493(1988) The DNA sequence and analysis of human chromosome 13.Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T., Ashwell R.I.S., Babbage |
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