| 产品详情 |
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| Product Name | Geminin, 1-209aa, Human, His tag, E Coli |
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| Description | MW: 27.6kDa (245aa), confirmed by MALDI-TOF. Purity >95% by SDS-PAGE. Geminin is a 25 kDa protein, which inhibits DNA replication and is degraded during the mitotic phase of the cell cycle. Geminin controls replication by binding to the licensing factor Cdt1, and is involved in neural differentiation. In addition, geminin directly interacts with Six3 and Hox homeodomain proteins during embryogenesis and inhibits their functions. |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [GMNN; Geminin; Geminin; DNA replication inhibitor; Gem; Geminin DNA replication inhibitor; OTTHuMP00000039393; RP3 369A17.3.] |
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| Gene, Accession, CAS # | GMNN; GMNN; Gem; MGORS6, Gene ID: 51053, Accession: NP_056979 |
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| Catalog # | MBS203067 |
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| Order / More Info | Geminin, 1-209aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | McGarry TJ. et al (1998) Cell. 93 (6):1043-53.; Pitulescu M. et al (2005) Cell Mol Life Sci. 62 (13):1425-33.; Luo L. et al (2004) Nature. 427 (6976):749-53; |
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