| 产品详情 |
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| Product Name | D-myo-Inositol-1,3,4-triphosphate (sodium salt) |
| Description | Purity >98%. The inositol phosphates play a critical role as small, soluble second messengers in transmission of cellular signals. D-myo -Inositol-1,3,4-triphosphate (Ins(1,3,4)-P3 ) is one of several different inositol oligophosphate isomers implicated in signal transduction. Ins(1,3,4)-P3 acts through the inhibition of Ins(3,4,5,6)-P4 kinase activity to increase the cellular level of Ins(3,4,5,6)-P4 and thus inhibit calcium-activated chloride channels. The levels of Ins(1,3,4)-P3 are in turn regulated by the levels of cytosolic free calcium. The receptor-mediated activation of phospholipase C (PLC) can be seen as the initiating event in this cascade, since PLC generates Ins(1,4,5)-P3 which releases calcium from intracellular storage reservoirs, leading to a dramatic but transient increase in the cytosolic concentration of free calcium. |
| Size | n/a |
| Concentration | n/a |
| Applications | n/a |
| Other Names | D-myo -inositol-1,3,4-tris (dihydrogen phosphate), trisodium salt, 1,3,4-IP3 (sodium salt), Ins(1,3,4)-P3 (sodium salt) |
| Gene, Accession, CAS # | n/a |
| Catalog # | LS-H7526 |
| Price | |
| Order / More Info | D-myo-Inositol-1,3,4-triphosphate (sodium salt) from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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