| 产品详情 |
| Edit |   |
|---|
| Product Name | D-myo-Inositol-2,4,5-triphosphate (sodium salt) |
|---|
| Description | Purity >98%. The inositol phosphates (InsP) play a critical role as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, D-myo -Inositol-2,4,5-triphosphate (sodium salt) (Ins(1,4,5)P3 ), more commonly referred to as IP3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(2,4,5)P3 is a metabolically stable analog of Ins(1,4,5)P3 that is commonly used to study Ca2+ signaling pathways. Ins(2,4,5)P3 acts as a partial agonist at rat hepatic IP3 receptors, exhibiting 65% of the maximal Ca2+ response obtained with Ins(1,4,5)P3 . |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | D-myo -inositol-2,4,5-tris (hydrogen phosphate), trisodium salt, 2,4,5-IP3 (sodium salt), Ins(2,4,5)P3 (sodium salt) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | LS-H7541 |
|---|
| Price | |
|---|
| Order / More Info | D-myo-Inositol-2,4,5-triphosphate (sodium salt) from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|